# Some Mathematical Questions in Biology—DNA Sequence Analysis

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*Robert M. Miura*

Several data banks around the world are accumulating DNA sequences at
a feverish rate, with tremendous potential for furthering our
knowledge of how biological systems code and pass on information. The
sophisticated mathematical analysis of that data is just beginning.
The Eighteenth Annual Symposium on Some Mathematical Questions
in Biology was held in conjunction with the Annual Meeting of the AAAS
and brought together speakers knowledgeable in both biology
and mathematics to discuss these developments and to emphasize the
need for rigorous, efficient computational tools.

These computational tools include biologically relevant definitions of
sequence similarity and string matching algorithms. The solutions for
some of these problems have great generality; the string matching
methods first developed for biological sequences have now been applied
to areas such as geology, linguistics, and speech recognition. There
is a great potential here for creating of new mathematics to
handle this growing data base, with new applications for many areas of
mathematics, computer science, and statistics.