eBook ISBN: | 978-1-4704-1964-6 |
Product Code: | MEMO/233/1096.E |
List Price: | $71.00 |
MAA Member Price: | $63.90 |
AMS Member Price: | $42.60 |
eBook ISBN: | 978-1-4704-1964-6 |
Product Code: | MEMO/233/1096.E |
List Price: | $71.00 |
MAA Member Price: | $63.90 |
AMS Member Price: | $42.60 |
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Book DetailsMemoirs of the American Mathematical SocietyVolume: 233; 2015; 87 ppMSC: Primary 60; 92
The goal of this work is to propose a finite population counterpart to Eigen's model, which incorporates stochastic effects. The author considers a Moran model describing the evolution of a population of size \(m\) of chromosomes of length \(\ell\) over an alphabet of cardinality \(\kappa\). The mutation probability per locus is \(q\). He deals only with the sharp peak landscape: the replication rate is \(\sigma>1\) for the master sequence and \(1\) for the other sequences. He studies the equilibrium distribution of the process in the regime where \[\ell\to +\infty,\qquad m\to +\infty,\qquad q\to 0,\] \[{\ell q} \to a\in ]0,+\infty[, \qquad\frac{m}{\ell}\to\alpha\in [0,+\infty].\]
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Table of Contents
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Chapters
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1. Introduction
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2. The Model
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3. Main Results
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4. Coupling
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5. Normalized Model
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6. Lumping
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7. Monotonicity
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8. Stochastic Bounds
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9. Birth and Death Processes
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10. The Neutral Phase
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The goal of this work is to propose a finite population counterpart to Eigen's model, which incorporates stochastic effects. The author considers a Moran model describing the evolution of a population of size \(m\) of chromosomes of length \(\ell\) over an alphabet of cardinality \(\kappa\). The mutation probability per locus is \(q\). He deals only with the sharp peak landscape: the replication rate is \(\sigma>1\) for the master sequence and \(1\) for the other sequences. He studies the equilibrium distribution of the process in the regime where \[\ell\to +\infty,\qquad m\to +\infty,\qquad q\to 0,\] \[{\ell q} \to a\in ]0,+\infty[, \qquad\frac{m}{\ell}\to\alpha\in [0,+\infty].\]
-
Chapters
-
1. Introduction
-
2. The Model
-
3. Main Results
-
4. Coupling
-
5. Normalized Model
-
6. Lumping
-
7. Monotonicity
-
8. Stochastic Bounds
-
9. Birth and Death Processes
-
10. The Neutral Phase